Ferutinin

Analytical standard

Synonym: 4-Oxy-6-(4-oxybenzoyloxy)dauc-8,9-en, 4-Hydroxy-benzoic acid (3R,3aS,4S,8aR)–1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)–4-azulenyl ester, Ferutinine, Tefestrol

CAS Number 41743-44-6             Empirical Formula (Hill Notation) C₂₂H₃₀O₄            Molecular Weight 358.47

Biochemical/physiological Actions

An ERα (estrogen receptor) agonist; phytoestrogen

Ferutinin is a naturally occurring non-steroidal phytoestrogen. It is a strong agonist for estrogen receptor (ER)α and agonist/antagonist for Erβ with IC50 values of 33.1 nM for ERα and 180.5 nM for Erβ. It has been shown to have both ionophoretic and apoptotic properties. It increases calcium permeability in the lipid bilayer and has been shown to improve bone regeneration in a rat study. It caused significant regression in tumor size in a mouse colon cancer model.

Properties

grade	analytical standard
assay	≥95.0% (HPLC)
form	Amorphous powder
storage temp.	2-8°C
color	white to beige

 

Price list:

Ferutinin (95%) 50 mg → 445 € (23805000 IRR)