Demethoxycurcumin

Analytical standard

Synonym: (E,E)–1-(4-Hydroxy-3-methoxyphenyl)–7-(4-hydroxyphenyl)–1,6-heptadiene-3,5-dione, Desmethoxycurcumin, Monodemethoxycurcumin

CAS Number: 22608-11-3

 Empirical Formula (Hill Notation) C₂₀H₁₈O₅     

 Molecular Weight 338.35

Biochemical/physiological Actions

Demethoxycurcumin (DMC) is a curcuminoide, and represents one of the major active components of curcumin products isolated from Curcuma sp. DMC inhibits LPS-induced nitric oxide (NO) production, and expression of iNOS and COX2 in RAW264.7 cells by blocking NF-kB activation. DMC also inhibits NF-kB dependent iNOS, TNFα and IL-1β expression in LPS-treated rat microglial cells. DMC suppresses expression of MMPs and ICAM-1 in MDA-MB-231 human breast cancer cells by inhibition of NF-kB.

Properties

grade	analytical standard
assay	≥95.0% (HPLC)
form	powder
storage condition	2-8°C protect from light
color	orange

Price list:

Demethoxycurcumin (95%) 25 mg → 150€ ( 35,000,000 IRR )

Demethoxycurcumin (95%) 100 mg → 450€ ( 90,000,000 IRR )