Demethoxycurcumin

Analytical standard

Synonym: (E,E)1-(4-Hydroxy-3-methoxyphenyl)7-(4-hydroxyphenyl)1,6-heptadiene-3,5-dione, Desmethoxycurcumin, Monodemethoxycurcumin

CAS Number 22608-11-3             Empirical Formula (Hill Notation) C20H18O5       Molecular Weight 338.35

demethoxycurcumin

Biochemical/physiological Actions

Demethoxycurcumin (DMC) is a curcuminoide, and represents one of the major active components of curcumin products isolated from Curcuma sp. DMC inhibits LPS-induced nitric oxide (NO) production, and expression of iNOS and COX2 in RAW264.7 cells by blocking NF-kB activation. DMC also inhibits NF-kB dependent iNOS, TNFα and IL-1β expression in LPS-treated rat microglial cells. DMC suppresses expression of MMPs and ICAM-1 in MDA-MB-231 human breast cancer cells by inhibition of NF-kB.

Properties

grade analytical standard
assay ≥95.0% (HPLC)
form powder
storage condition -20°C protect from light
color orange

 

Price list:

Demethoxycurcumin (95%) 25 mg → 121 € (6322000 IRR)

Demethoxycurcumin (95%) 100 mg →330 € (17720000 IRR)