Curcumin

Analytical standard

Synonym: (E,E)–1,7-bis(4-Hydroxy-3-methoxyphenyl)–1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3

CAS Number: 458-37-7

Empirical Formula (Hill Notation): C₂₁H₂₀O₆     

Molecular Weight: 368.38

Biochemical/physiological Actions

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Properties

grade	experimental
assay	≥95.0 % (HPLC ) , 75.0%
form	powder
storage temp.	2-8°C
color	orange

 

Price list:

Curcumin (75%) 100 mg → 60 € ( 16,000,000 IRR)

Curcumin (95%) 50 mg   → 140 € (32,000,000 IRR)

Curcumin (95%) 500 mg → 310 € (115,000,000 IRR)